How to Manage Metabolic Disorders? Introduction Before knowing about metabolic disorders you must know what is normal metabolism? Metabolism is defined as the group of chemical reactions that sustains life in an organism. Any alteration in these chemical reactions can disturb the functioning of the body and results in metabolic disorders. Usually, these metabolic disorders are inherited and occur due to any genetic anomaly. This defective gene causes deficiency of the specific enzyme disrupting the normal functions of the body.