The Role of Immune System in Hepatitis Management Hepatitis is an infectious disease of the liver and is caused by five kinds of viruses. Therefore, hepatitis is also known to be of five types, namely hepatitis A, hepatitis B, hepatitis C, hepatitis D, and hepatitis E. the body’s response towards all these forms of hepatitis because they affect the body differently. The body’s response towards any infectious disease is regulated by the immune system which responds via a systematic process.