What is EPO THERAPY?
Anaemia is defined as a decrease in the oxygen carrying capacity of blood, measured in the laboratory as a low haemoglobin concentration, or a low hematocrit (the percentage of the blood volume that is occupied by red blood cells or erythrocytes). In a normal person, the haemoglobin is approximately 13 grams per decilitre and the hematocrit is approximately 40%.
Anaemia is not a disease as such, but a reflection of some other problem. It occurs when the balance between the normal rates of blood loss and blood production is disturbed. There are three basic mechanisms by which this occurs: (1) blood loss, (2) excessive destruction of red blood cells (haemolysis), and (3) abnormally low production of red blood cells by the bone marrow.
In a person with normal renal function, the finding of anaemia on routine blood analysis would prompt a work-up to determine the ultimate cause. In chronic renal failure, anaemia is almost always present, and can be a result of any of the mechanisms listed above. However, the typical "anaemia of chronic renal insufficiency" is a result of a decreased production of red blood cells by the bone marrow.
This defect in red blood cell production is largely explained by the inability of the failing kidneys to secrete the hormone erythropoietin. This hormone is a necessary stimulus for normal bone marrow to produce red blood cells. In addition, other factors associated with renal failure, including the accumulation of so-called uremic toxins, may play a role in depressing bone marrow function. Excess stores of aluminium may accumulate in the bone marrow of long term dialysis patients and can contribute to anaemia as well.
Blood loss and red blood cell destruction also frequently contribute to the anaemia in patients with renal failure. Platelets, which are small constituents of blood which aid in blood clotting; do not work normally in uraemia. The defective blood clotting seen in uraemia makes bleeding more common. Rapid bleeding from an ulcer in the gastrointestinal tract, for example, causes a rapid decrease in the hematocrit and is a medical emergency. Very slow loss of blood can also cause anaemia by depleting the body’s stores of iron, which the bone marrow uses to produce blood cells.
Excessive destruction of red blood cells is also seen in advanced renal failure. Normally, red blood cells survive for about four months before being destroyed. This life span is reduced in renal failure, probably because of chemical effects of uraemia and decreased flexibility of the red blood cells. This haemolysis is usually mild and a person with a normal bone marrow could easily compensate for it by increasing red blood cell production. However, in renal failure, the bone marrow’s capacity to compensate is diminished.
What is the Role of Haemodialysis in the Anaemia of Chronic Renal Failure?
The effectiveness of dialysis in reversing any complication of uraemia depends on the nature of that complication. Those disturbances which are due to accumulation of a uremic toxin may be reversible if that toxin is dialyzable and if the removal rate by dialysis outstrips its generation rate. Some improvement in red blood production is seen with initiation of dialysis, probably by decreasing the toxic effect of uraemia on the marrow. Dialysis, however, does not replace the hormone producing functions of the kidney and therefore does not by itself correct the main cause of anaemia, namely deficient production of erythropoietin. Dialysis does correct the bleeding tendency seen in uraemia, but not to normal.
Dialysis itself may also contribute to the anaemia. Iron deficiency can result from unavoidable dialyzer blood loss, clotted dialysis membranes, and frequent blood sampling. Haemolysis may occur if there are problems with the dialysate (temperature problems, contamination with aluminium, fluoride, copper, chlorine, or chloramines). Folate, a water soluble vitamin necessary for normal red blood cell production, is dialyzable. Generally, dialysis patients are given oral supplementation with folic acid in case their normal diet does not supply them with sufficient folate to keep up with its loss through dialysis.
Most patients tolerate chronic anaemia fairly well. In an otherwise healthy patient with chronic renal failure, a hematocrit of approximately 25% is typical. The presence of other medical problems, particularly heart and lung disease, can decrease a patient’s ability to tolerate a lower blood count. Patients who have undergone bilateral kidney removal (nephrectomise) often have hematocrits which are significantly lower, probably because they cannot make any erythropoietin at all. Patients whose kidney failure is a result of polycystic kidney disease generally do not have anaemia.
The treatment of the anaemia of chronic renal failure has changed dramatically in recent years. Until recently, the principal treatments were transfusion of red blood cells and administration of the hormone testosterone. Although transfusions will rapidly correct a low blood count, repeated transfusions are associated with some problems, including iron overload, the development of certain antibodies, and the possibility of viral infections. Testosterone may stimulate red blood cell production by the bone marrow, but the effect is generally small, and its use is often associated with virilising side effects.
Effective Herbal Remedy to Control Sugar Level
This herbal blend called Dia-beta plus is going to work slowly. Dia-beta plus is not going to lower down sugar immediately or cause hypoglycemia. The effects are slow but sustained and can be monitored. Over the period of time, You may need to reduce the dosage of your other drugs, supplements or herbs for diabetes being used.
Dia-beta plus is a mixture of various herbs for diabetes, which are described in Ayurveda for taking care of diabetes naturally. The herbs not only help to control sugar levels but also help to rejuvenate overall health, bring back stamina and help to overcome fatigue. Dia-beta plus contains herbs like momordica, Gymnema, Salacia, Pterocarpus marsupium which are long know to have beneficial effects in diabetes.The herbs are not only good to control sugar levels but also excellent for preventing diabetic neuropathy.
This product has its roots in Ayurveda-ancient herbal healthcare system of India . According to Ayurveda the balance of 3 energies- Vata, Pitta and Kapha (Kinetic, Thermal and Potential energy) in the body is a disease free state whereas their imbalance causes diseases. In Ayurveda, imbalance in “Vata” and “Kapha” is considered as root cause of diabetes. Herbs in this formula control both “Vata” and “Kapha” and thus good in controlling sugar levels.
Herbs in Dia-beta Plus
Dia-beta Plus is purely a herbal formulation without any chemicals added into it. The ingredients are frequently used in Ayurvedic system of medicine since 5,000 B.C. without any side effects. Although there are many herbal products for diabetes, but this one is unique in bringing down sugar levels under control without causing side effects and without causing sharp fluctuation in sugar levels.
Ingredients of Dia-beta Plus
|S. No.||Herb Used||Latin Name||Quantity|
|1.||Gurmaar||Gymnema sylvestrae||150 mg|
|2||Karela||Momordica charantia||150 mg|
|3.||Saptrangi||Salacia oblonga||50 mg|
|4.||Vizaysaar||Pterocarpus marsupium||50 mg|
|5.||Ashwagandha||Withania somnifera||50 mg|
|6.||Tulsi||Ocimum tenuiflorum||50 mg|
Ingredients of Dia-beta Plus
1. Gurmaar (Gymnema sylvestrae)
In Hindi language, Gurmaar means "The sugar killer". It is a twine which is known since ages in Ayurveda for its sugar controlling activity. Recent studies show that it contains Gymnemic acid molecules responsible for its anti-diabetic action. They bind with glucose molecules in the intestines and inhibit their entry into the blood stream. Thus it is effective in controlling sugar levels. This is a perfect herb for sugar control.
2. Karela (Momordica charantia)
Commonly known as bitter gourd. It is very popular for it's anti-diabetic properties. It's also rich in micronutrients which are required for prevention of complications of diabetes. We have a juice form of momordica herb as well. Read more about our product Karela Saar The products like Diabeta plus, Karela Saar, Ashwagandha, Shilajit can all be used together to combat diabetes with herbal remedies.
3. Vizaysaar (Pterocarpus marsupium)
Vizaysaar is a big tree whose bark is very useful for diabetes. The bark of the tree is made into a wooden glass and the glass is termed as “The miracle care for diabetes”. Some water is kept in the wooden glass overnight and is consumed early morning by diabetes patients. The color of the water changes to brown and glass is changed after around 1 month when the water color does not change. Diabeta Plus contains extract of bark of this miracle tree.
4. Saptrangi (Salacia oblonga)
Salacia oblonga is a wonderful remedy for diabetes. It is also a tree whose bark is effective in controlling diabetes. It is extensively studied in the western herbal schools now a days, but in Ayurveda it is being used since ages.
- For Non Insulin Dependent - 2 capsules twice daily, 1/2 hour before meals, with water.
- For Insulin Dependent - 4 - 6 capsules twice daily, 1/2 hour before meals, with water.
To buy Dia-beta Plus, please visit store.planetayurveda.com/dia-beta-plus-capsules.html
Other Supplements Good to be Used With Diabeta Plus
Ashwagandha (Withania somnifera)
Ashwagandha is adaptogenic, relieves anxiety and stress. It is also an effective anti-inflammatory. Ashwagandha is a useful herb especially for diabetic neuropathy, weakness, fatigue and weight loss due to diabetes. It improves overall well being.
Tulsi (Ocimum sanctum)
It is popularly known as 'The Holy Basil' is a sacred plant according to Hindu mythology. People in India worship this plant as it has tremendous medicinal properties. Regular use of leaves of this plant controls blood sugar levels very effectively. It is also useful in many types of cancers, viral and bacterial infections, sore throat, cough and cold etc.
Diabeta Plus capsule contains effective Herbs for Diabetes control. It Controls Sugar Levels Naturally. The herbs for Sugar control are without any additives or preservatives.It can be very useful as an very effective herbal treatment for Diabetes.
A very useful and effective natural treatment for Diabetic Neuropathy. Although there are a lot of Herbal Products for Diabetes, but the unique combination of various herbs in Diabeta Plus has made it a very different and a very useful herbal product for diabetes.
Ashwagandha and Shilajit Capsules are some other herbal supplements which can be used along with Dia-beta Plus to combat diabetic neuropathy. Neuropathy responds quickly to this herbal combination. Ashwagandha is used 500 mg capsules in twice daily dosage to combat Diabetic Neuropathy effectively and other complications of diabetes.