Pannalapatiryadi Ghrita – Medicinal Properties, Ingredients, Indications, Dosage & More

Introduction

Pannalapatiryadi Ghrita is a classical Ayurvedic medicated ghee formulation indicated in Visha Roga (toxic conditions and poisoning). This formulation is a complex polyherbal preparation composed of Kwatha (decoction), Svarasa (fresh juices), and Kalka (herbal paste) processed in Murchita Goghrita (purified cow’s ghee). It is designed to neutralize toxins, support vital organs, and restore systemic balance. The formulation includes multiple Vishaghna (anti-toxic), Rasayana (rejuvenative), and Deepana-Pachana (digestive) herbs, making it highly effective in managing both acute and chronic toxic conditions.

Reference Shloka

पाणलं चाथ पंचांग कापास्याः पाटला तथा।
पाठा जया गारुडी च पंचांगं च शिरीषजम् ।।
बिल्वं मधूकं वसुकं सर्पगन्धा फलत्रयम्।
नील्युशीरे च एतैस्तु कषायं कारयेद्भिषक् ।।
अपामार्गो व्याघ्रपादी नेयबल्ली विम्बिपत्रकम् ।।
दशपुष्पाणि ब्रह्मी च एतेषां स्वरसस्तथा।।
स्वरसग्रहणार्थ तु नीरं योज्यं कषायकम्।
पूर्वोक्तस्येति तु मतं ज्ञेयं च विषहारिणाम् ।।
हिंगुर्वचा च लशुनः यष्टीमधुकमेव च।
अश्वगन्धा जीरके द्वे मृद्धीका चन्दनं तथा।।
वरा कुष्ठं च तक्कोलं पद्मवीजं कटुत्रयम्।
कल्कार्थ चापि दत्वाऽथ साधयेद्धृतमुत्तमम् ।।
सारमेयविषं हन्ति गोपनीयं प्रयत्नतः ।।

Composition

I. Kwatha Dravyas (Decoction Ingredients)

Panala — 80 gm
Karpasa Panchanga (Gossypium herbaceum — Cotton plant whole) — 80 gm
Patala (Stereospermum suaveolens — Trumpet flower tree) — 80 gm
Patha (Cissampelos pareira — Velvetleaf) — 80 gm
Agnimantha (Clerodendrum phlomidis — Arni) — 80 gm
Garudi (Pergularia daemia — Trellis-vine) — 80 gm
Sirisha Panchanga (Albizia lebbeck — Siris whole plant) — 80 gm
Bilva (Aegle marmelos — Bael) — 80 gm
Madhuka (Madhuca longifolia — Mahua) — 80 gm
Punarnava (Boerhavia diffusa — Spreading hogweed) — 80 gm
Sarpagandha (Rauvolfia serpentina — Indian snakeroot) — 80 gm
Haritaki (Terminalia chebula — Chebulic myrobalan) — 80 gm
Vibhitaki (Terminalia bellirica — Beleric myrobalan) — 80 gm
Amalaki (Emblica officinalis — Indian gooseberry) — 80 gm
Nili (Indigofera tinctoria — Indigo) — 80 gm
Usira (Vetiveria zizanioides — Vetiver) — 80 gm
Water — 10.24 litres

II. Svarasa Dravyas (Fresh Juice Ingredients)

Apamarga (Achyranthes aspera — Prickly chaff flower) — 80 gm
Vyaghrapadi — 80 gm
Neyavalli — 80 gm
Bimbi Patra (Coccinia grandis — Ivy gourd leaves) — 80 gm
Vishnukranta Pushpa (Evolvulus alsinoides — Dwarf morning glory) — 80 gm
Durva Pushpa (Cynodon dactylon — Bermuda grass flowers) — 80 gm
Bhringaraja Pushpa (Eclipta alba — False daisy) — 80 gm
Shakralata Pushpa — 80 gm
Varahi Pushpa — 80 gm
Bhadrika Pushpa — 80 gm
Sahadevi Pushpa (Vernonia cinerea) — 80 gm
Shashakarni Pushpa — 80 gm
Lakshmana Pushpa (Ipomoea sepiaria) — 80 gm
Lajjalu Pushpa (Mimosa pudica — Touch-me-not) — 80 gm
Brahmi (Bacopa monnieri — Water hyssop) — 80 gm
Water — 10.24 litres

III. Ghrita Dravya

Murchita Goghrita (Processed Cow’s Ghee) — 1280 gm

IV. Kalka Dravyas (Herbal Paste Ingredients)

Hingu (Ferula asafoetida — Asafoetida) — 20 gm
Vacha (Acorus calamus — Sweet flag) — 20 gm
Lasuna (Allium sativum — Garlic) — 20 gm
Yashtimadhu (Glycyrrhiza glabra — Licorice) — 20 gm
Ashwagandha (Withania somnifera — Indian ginseng) — 20 gm
Jiraka (Cuminum cyminum — Cumin) — 20 gm
Krishna Jiraka (Nigella sativa — Black cumin) — 20 gm
Draksha (Vitis vinifera — Raisins) — 20 gm
Chandana (Santalum album — Sandalwood) — 20 gm
Haritaki (Terminalia chebula) — 20 gm
Vibhitaki (Terminalia bellirica) — 20 gm
Amalaki (Emblica officinalis) — 20 gm
Kushta (Saussurea lappa — Costus) — 20 gm
Takkola (Illicium verum — Star anise) — 20 gm
Padmabija (Nelumbo nucifera — Lotus seeds) — 20 gm
Sunthi (Zingiber officinale) — 20 gm
Pippali (Piper longum) — 20 gm
Maricha (Piper nigrum) — 20 gm

Method Of Preparation

First, the Kwatha (decoction) is prepared by boiling Kwatha Dravyas (decoction ingredients) in water and reducing it to one-fourth. Separately, Kalka Dravyas (paste ingredients) are made into a fine paste and mixed thoroughly with Murchita Goghrita (processed cow’s ghee). Then the prepared decoction is added to this mixture. Next, Svarasa Dravyas (juice ingredients) are processed to extract their juices (or reduced decoction where necessary) and added to the mixture. The entire preparation is then subjected to mild heating following classical Sneha Paka Vidhi (medicated ghee preparation process) until only medicated ghrita remains. After achieving proper Sneha Siddhi Lakshanas (signs of completion), the formulation is filtered and stored in clean, wide-mouthed glass containers.

Method Of Use

Internal Administration

Internal administration

Dose

10 gm daily or as advised

Anupana

Milk

Pharmacological Actions

Vishaghna – neutralizes toxins
Deepana – improves digestive fire
Pachana – digests metabolic toxins
Rasayana – rejuvenates tissues
Shothahara – reduces inflammation
Balya – strengthens body systems

Indications

Visha Roga (poisoning and toxic conditions)
Chronic toxin accumulation
Systemic toxicity affecting multiple organs
Weak immunity due to toxic load

Therapeutic Properties

This formulation is a comprehensive anti-toxic preparation. Sirisha (Albizia lebbeck) and Apamarga (Achyranthes aspera) are well-known Vishaghna herbs that help neutralize toxins. Triphala—Haritaki (Terminalia chebula), Vibhitaki (Terminalia bellirica), and Amalaki (Emblica officinalis)—supports detoxification and digestion. Sarpagandha (Rauvolfia serpentina) provides calming and systemic regulatory effects. Brahmi (Bacopa monnieri) enhances nervous system stability, while Ashwagandha (Withania somnifera) improves strength and resilience. The inclusion of multiple floral juices enhances subtle detoxification and systemic cleansing. Goghrita (cow’s ghee) acts as a Yogavahi (carrier), ensuring deep tissue penetration and nourishment.

Precautions

Should be used strictly under medical supervision
Use cautiously in pregnancy and lactation
Monitor for digestive tolerance
Not advised in individuals with weak digestion without prior Deepana therapy

Conclusion

Pannalapatiryadi Ghrita is a highly potent and complex Ayurvedic formulation designed for managing Visha Roga (toxic conditions). Its multi-layered preparation involving decoction, fresh juices, and herbal paste enhances its therapeutic efficacy. When administered properly, it helps neutralize toxins, restore physiological balance, and strengthen overall health, making it a valuable formulation in Ayurvedic toxicology and systemic detoxification.