How to Cure Scleroderma with Home Remedies? Scleroderma is the medical term used for the disease which causes hardening and thickening of skin connective tissues. Many patients with Scleroderma feel uncomfortable and over-self-conscious. This disease shows symptoms such as dry, stiff and itchy skin, red spots on hands and face, dry mouth, and fatigue. It’s an autoimmune disease due to which the symptoms vary from person to person. There are a number of drugs such as Penicillamine, and glucocorticoids that